Enalapril Maleate
Ka morao
Enalapril Maleate
Tlhaloso
Enalapril (maleate) (MK-421 (maleate)), metabolite e sebetsang ea enalapril, ke angiotensin-converting enzyme (ACE) inhibitor.
Ho Vivo
Enalapril (MK-421) ke prodrug e leng ea angiotensin-converting enzyme (ACE) inhibitor sehlopha sa meriana.E ka potlako metabolized ka sebete ho enalaprilat ka mor'a tsamaiso ea molomo.Enalapril (MK-421) ke inhibitor e matla, e nang le tlhōlisano ea ACE, enzyme e ikarabellang bakeng sa phetoho ea angiotensin I (ATI) ho angiotensin II (ATII).ATII e laola khatello ea mali 'me ke karolo ea bohlokoa ea renin-angiotensin-aldosterone system (RAAS).Enalapril e ka sebelisoa ho phekola khatello ea mali e hlokahalang kapa e nchafatsang le matšoao a ho hloleha ha pelo.
Polokelo
Phofo | -20°C | 3 lilemo |
4°C | lilemo tse 2 | |
Ka solvent | -80°C | Likhoeli tse 6 |
-20°C | 1 khoeli |
Sebopeho sa lik'hemik'hale
Tlhahiso18Merero ea Tlhahlobo ea Boleng e amohetsoeng4, le6merero e tlas'a tumello.
Sistimi e tsoetseng pele ea boleng ba machaba e thehile motheo o tiileng oa thekiso.
Tlhokomelo ea boleng e tsamaisana le potoloho eohle ea bophelo ba sehlahisoa ho netefatsa boleng le phello ea kalafo.
Sehlopha sa Litaba tsa Taolo ea Setsebi se tšehetsa litlhoko tsa boleng nakong ea kopo le ngoliso.