Matlapa a Atorvastatin calcium le rosuvastatin calcium ke lithethefatsi tse theolang lipid, 'me ka bobeli ke tsa litlhare tse matla tsa statin.Liphapang tse khethehileng ke tse latelang:

1. Ho ea ka pono ea pharmacodynamics, haeba lethal dose le lekana, phello ea ho theola lipid ea rosuvastatin e matla ho feta ea atorvastatin, empa bakeng sa lethal dose le tloaelehileng le khothalletsoang ke tleliniki, phello ea ho theola lipid ea lithethefatsi tsena tse peli ha e le hantle e tšoana. ;

2. Mabapi le meriana e thehiloeng bopaking, kaha atorvastatin e 'nile ea e-ba' marakeng pejana, ho na le bopaki bo bongata ba atorvastatin ka mafu a pelo le cerebrovascular ho feta rosuvastatin;3. Mabapi le metabolism ea lithethefatsi, ho na le phapang e itseng pakeng tsa tse peli.Atorvastatin e sebelisoa haholo ke sebete, athe karolo e nyane feela ea rosuvastatin e hlahisoa ke sebete.Ka hona, atorvastatin e atisa ho sebelisana le lithethefatsi tse bakoang ke li-enzyme tsa lithethefatsi tsa sebete;

4. Atorvastatin e ka ba le litlamorao tse mpe sebeteng ho feta rosuvastatin.Ha ho bapisoa le atorvastatin, litlamorao tsa rosuvastatin li kanna tsa hlaha liphiong.Ka bokhutšoanyane, atorvastatin le rosuvastatin ka bobeli ke lithethefatsi tse matla tse fokotsang lipid, 'me ho ka ba le liphapang ho metabolism ea lithethefatsi, tšebelisano ea lithethefatsi le litlamorao tse mpe.