Lilemong tsa morao tjena, thekiso eaapixabanli eketsehile ka potlako, 'me' maraka oa lefats'e o se o fetilerivaroxaban.Hobane Eliquis (apixaban) e na le molemo ho feta warfarin ho thibela stroke le mali, le Xarelto (Rivaroxaban) e bontšitse feela ho se be tlase.Holim'a moo,Apixabanha e hloke liphetoho tse rarahaneng tsa litekanyetso, 'me meriana e bonolo haholoanyane.Letoto lena la go tlhoka mesola e bakilengrivaroxabanho lahleheloa ke mobu 'marakeng oa US.

Leha ho le joalo, naheng ea China,rivaroxabane na le matšoao a mangata lefatšeng ka bophara le naheng ea China.Nako ea ho fela ha tokelo ea molao earivaroxabane haufi, 'me ho fumaneha ha moriana ho tla etsa hore baahi barivaroxabanlithethefatsi tse akaretsang ho feta haholo tsaApixaban.

Ho latela data ea Xianda, thekiso ea 'maraka ea lapeng ea rivaroxaban ka 2018 e ne e le li-yuan tse limilione tse likete tse 2.8.Ho ea ka phatlalatso ea Huahai Pharmaceutical, lipetlele tsa malapeng thekiso earivaroxabanka 2018 e ne e le li-yuan tse limilione tse likete tse 1.527.

Ehlile, lethathamo la lithethefatsi tse tloaelehileng le tla lebisa ho theoheng ho hoholo ha theko ea letsatsi le le leng larivaroxaban.Ho ela hloko hore har'a li-NOAC tsohle, litokelo tsa molao tsarivaroxabanlik'hemik'hale li felloa ke nako ka 2020 hang-hang (lipatente tsaapixabanle dabigatran etexilate li telele Ka nako e telele), ha ho pelaelo hore e tla ba molemo ho nts'etsopele e felletseng earivaroxabanlithethefatsi tse akaretsang ho nkela warfarin sebaka.Haeba theko ea letsatsi le letsatsi earivaroxabanlithethefatsi tsa generic li qalisoa ho tloha ho 27.6 yuan ho ea ho 2.76 yuan, mokhoa ona o tla boela o matlafatsoe.

Palo ea likopo tse nahanang feela bakuli ba atrial fibrillation (AF) le eona ea hlolla.Palo ea bakuli ba atrial fibrillation Chaena e ka ba limilione tse 10, bao ba ka bang limilione tse 2 ba nang le valvular atrial fibrillation le ba ka bang limilione tse 7 bakeng sa non-valvular atrial fibrillation.Patlisiso ka 2016 Ho fumanoe hore sekhahla sa tlhokomeliso ea atrial fibrillation naheng ea Mainland China ke 40%, mme sekhahla sa anticoagulation ke 30%.Rivaroxaban e bonolo ho e sebelisa, ha e hloke ho lekoa khafetsa ha matšoao a coagulation, mme sekhahla sa anticoagulation le sona se tla ntlafatsoa haholo.Ho boleloa esale pele hore moriana o akaretsang oarivaroxabane tla ba Mainland China.Boholo ba 'maraka bo sebelisoang ho bakuli ba nang le "non-valvular atrial fibrillation" le "atrial fibrillation": bakuli ba limilione tse 7 * 30% anticoagulation rate * 50% sekhahla sa ho kenella * 2.76 yuan / letsatsi * matsatsi a 365 = li-yuan tse limilione tse 157.

Ntle le moo, litebello tsa 'maraka tsa thibelo le kalafo ea bakuli ba VTE ha li nyenyefatsoe.Ho ea ka lipalo-palo tsa Setsi sa Thibelo le Kalafo sa VTE United States, palo ea bakuli ba VTE United States e phahame ho feta 900,000 selemo le selemo, 'me palo ea batho ba shoang ka VTE e fihla ho 60,000 ho 100,000,' me ho na le mathata a nako e telele (A kang DVT) bakuli ba ne ba etsa karolo ea 50%, 'me palo ea ho khutlela morao nakong ea lilemo tse 10 e ne e le 33%.

Ka lebaka la ho tsofala ha baahi ba Chaena, 'me palo ea baahi e feta makhetlo a 4 ho feta United States (batho ba limilione tse likete tse 1.395).Ho ka boleloa esale pele hore ho na le bakuli ba VTE ba limilione tse 3.6 Chaena selemo se seng le se seng.Ho nka hore sekhahla sa kalafo sa likhoeli tse 3 sarivaroxabanke 80%, boholo ba 'maraka ke: bakuli ba limilione tse 3.6 * 80% sekhahla sa phekolo * 2.76 yuan / letsatsi * matsatsi a 92 = li-yuan tse limilione tse 731.

Ka hona, ha ho baloa matšoao a mabeli a AF le VTE feela, boholo ba mmaraka oa lehae oa rivaroxaban generic drug e haufi le li-yuan tse limilione tse likete tse 2.Ho lekane ho etsa hore lik'hamphani tsa malapeng tsa meriana li potlakele ho etsa kopo ea lethathamo.

Rona,Changzhou Pharmaceutical Factory, hape hlahisaapxiabanlerivaroxban, 'me ka bobeli ba na le DMF.Rivaroxabane ntse e sebetsa ka ho sebelisa CEP le WC.