Calcium ea pitavastatin

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Calcium ea pitavastatin Hypercholesterolemia Ka Ntlong      


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TLHAKISO SEHLAHISO

匹伐他汀钙 Pitavastatin 147526-32-7 Ka Ntlong
PI-5 3800-06-4 Ka Ntlong
PI-6 145516-11-4 Ka Ntlong
PI-7 121660-11-5 Ka Ntlong

 

Tlhaloso

Pitavastatin Calcium (NK-104 hemicalcium) ke matla a matla a hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor.Pitavastatin Calcium (NK-104 hemicalcium) e thibela k'holeseterole synthesis ho tloha acetic acid ka IC50 ea 5.8 nM liseleng tsa HepG2.Pitavastatin Calcium ke e sebetsang hantle ea hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer.Ts'ebetso e khahlanong le mofetše.

 

Ka morao

Pitavastatin Calcium ke inhibitor ea tlholisano ea enzyme ea HMGCR (HMG-CoA reductase) e fella ka ho fokotseha ha LDL cholesterol synthesis.Liphuputso tse ling li bontša hore pitavastatin e ka hatella tlhahiso ea oksijene liseleng tsa endothelial ka ho thibela NADPH oxidase.Ntle le moo, pitavastatin e fokotsa polelo ea eNOS mRNA ha e ntse e eketsa karabelo e itšetlehileng ka NO e hlohlellelitsoeng ke acetylcholine le calcium ionophore, A23187.Ho feta moo, pitavastatin e thibela ho phahama ha likanale tsa potasiamo tse kentsoeng k'halsiamo ka ho theola boemo ba k'holeseterole liseleng.

 

Polokelo

4°C, sireletsa khanyeng

*Ka solvent : -80°C, likhoeli tse 6;-20°C, khoeli e le 'ngoe (sireletsa leseli)

 

Sebopeho sa lik'hemik'hale

Pitavastatin Calcium

Lintlha tse amanang le Biological

Pitavastatin Calcium2

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