Abrocitinib

Tlhaloso e Khutšoanyane:

Lebitso la API Pontsho Moqapi Letsatsi la Phello ea Patent(US)
Abrocitinib Dermatitis ea Atopic Pfizer Hlakola.11, 2034


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TLHAKISO SEHLAHISO

Abrocitinib ke molek'hule ea molomo, e nyenyane, Janus kinase (JAK) 1 inhibitor e nts'etsopele bakeng sa phekolo ea batho ba baholo le bacha ba nang le dermatitis ea atopic e itekanetseng ho isa ho e matla.

Abrocitinib e ntse e etsoa lipatlisiso tekong ea bongaka ea NCT03796676 (JAK1 Inhibitor With Medicated Topical Therapy in Adolescents With Atopic Dermatitis).

Abrocitinib hajoale e ntse e ntlafatsoa ke Pfizer bakeng sa kalafo ea atopic dermatitis (eczema).Ke sethibela sa ho etsa lipatlisiso ka molomo hang ka letsatsi Janus kinase 1 (JAK1) inhibitor.

Atopic dermatitis (AD) ke lefu la letlalo le rarahaneng, le sa foleng, le nang le ho ruruha le khetholloang ke ho hlohlona ho matla, le maqeba a eczematous le amang karolo ea 25% ea bana le 2% ho isa ho 3% ea batho ba baholo lefatšeng ka bophara.Abrocitinib ke inhibitor e khethiloeng ea enzyme ea Janus kinase-1 (JAK1) e thibelang mokhoa oa ho ruruha.Ka hona, re ne re ikemiselitse ho hlahloba katleho le polokeho ea abrocitinib bakeng sa AD e itekanetseng ho isa ho e matla.

Abrocitinib ka tekanyo ea 100 mg kapa 200 mg ke sethethefatsi se sebetsang hantle, se mamelloang hantle, le se tšepisang ho phekola bakuli ba nang le atopic dermatitis e itekanetseng ho isa ho e matla.Leha ho le joalo, tlhahlobo e ne e rata katleho ea abrocitinib 200 mg ho feta 100 mg, empa litla-morao tse kang ho nyekeloa ke pelo le hlooho li ka etsahala haholo ka 200 mg.

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