Baloxavir Marboxil 1985606-14-1
Ka morao
Baloxavir marboxil ke setlhare se thibelang likokoana-hloko 'me ke endonuclease inhibitor.Likhotong le litšoeneng, khatello ea mali ea lithethefatsi e fokotsehile ho feta tekanyo e fokolang ea ho lemoha tsamaisong e le 'ngoe ea molomo ea lithethefatsi.Mefuteng ea tšoaetso ea preclinical influenza A le B (ho kenyeletsoa le mefuta e hanyetsanang le lithethefatsi tse seng li ntse li le teng), Baloxavir marboxil e na le phello e itseng.
Lintho tsa Lik'hemik'hale
Polokelo | Boloka ho -20°C |
M.Wt | 571.55 |
Cas No. | 1985606-14-1 |
Foromo | C27H23F2N3O7S |
Litlhaloso tse tšoanang | S-033188 |
Solubility | E qhibiliha ka DMSO |
Lebitso la Lik'hemik'hale | ((R)-12-((S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl)-6,8-dioxo-3,4,6,8, 12,12a-hexahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-yl)oxy)methyl methyl carbonate |
SDF | Khoasolla SDF |
Canonical POSISO | O=C1C=CN(N([C@]2(N(C3=O)CCOC2)[H])[C@H]4C5=CC=C(C(F)=C5CSC6=CC=CC=C46) F)C3=C1OCOC(OC)=O |
Boemo ba ho Romela | Tlhahlobo ea tharollo ea mohlala: sekepe se nang le leqhoa le leputsoa.Mefuta eohle e meng e fumanehang: sekepe se nang le RT, kapa leqhoa le leputsoa ha le kopa. |
Malebela a akaretsang | Bakeng sa ho fumana solubility e phahameng, ka kopo futhumatsa tube ka 37 ° C 'me u e sisinye ka bateng ea ultrasonic ka nakoana.Tharollo ea setoko e ka bolokoa ka tlase ho -20 ° C ka likhoeli tse 'maloa. |
Sebopeho sa lik'hemik'hale
Tlhahiso18Merero ea Tlhahlobo ea Boleng e amohetsoeng4, le6merero e tlas'a tumello.
Sistimi e tsoetseng pele ea boleng ba machaba e thehile motheo o tiileng oa thekiso.
Tlhokomelo ea boleng e tsamaisana le potoloho eohle ea bophelo ba sehlahisoa ho netefatsa boleng le phello ea kalafo.
Sehlopha sa Litaba tsa Taolo ea Setsebi se tšehetsa litlhoko tsa boleng nakong ea kopo le ngoliso.