Baloxavir Marboxil 1985606-14-1

Tlhaloso e Khutšoanyane:

Lebitso la API Pontsho Moqapi Letsatsi la Phello ea Patent(US)
Baloxavir Marboxil 1985606-14-1 Mohatselaane Shionogi & Roche Sep.21,2031


Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

TLHAKISO SEHLAHISO

Ka morao

Baloxavir marboxil ke setlhare se thibelang likokoana-hloko 'me ke endonuclease inhibitor.Likhotong le litšoeneng, khatello ea mali ea lithethefatsi e fokotsehile ho feta tekanyo e fokolang ea ho lemoha tsamaisong e le 'ngoe ea molomo ea lithethefatsi.Mefuteng ea tšoaetso ea preclinical influenza A le B (ho kenyeletsoa le mefuta e hanyetsanang le lithethefatsi tse seng li ntse li le teng), Baloxavir marboxil e na le phello e itseng.

Lintho tsa Lik'hemik'hale

Polokelo Boloka ho -20°C
M.Wt 571.55
Cas No. 1985606-14-1
Foromo C27H23F2N3O7S
Litlhaloso tse tšoanang S-033188
Solubility E qhibiliha ka DMSO
Lebitso la Lik'hemik'hale ((R)-12-((S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl)-6,8-dioxo-3,4,6,8, 12,12a-hexahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-yl)oxy)methyl methyl carbonate
SDF Khoasolla SDF
Canonical POSISO O=C1C=CN(N([C@]2(N(C3=O)CCOC2)[H])[C@H]4C5=CC=C(C(F)=C5CSC6=CC=CC=C46) F)C3=C1OCOC(OC)=O
Boemo ba ho Romela Tlhahlobo ea tharollo ea mohlala: sekepe se nang le leqhoa le leputsoa.Mefuta eohle e meng e fumanehang: sekepe se nang le RT, kapa leqhoa le leputsoa ha le kopa.
Malebela a akaretsang Bakeng sa ho fumana solubility e phahameng, ka kopo futhumatsa tube ka 37 ° C 'me u e sisinye ka bateng ea ultrasonic ka nakoana.Tharollo ea setoko e ka bolokoa ka tlase ho -20 ° C ka likhoeli tse 'maloa.

Sebopeho sa lik'hemik'hale

Baloxavir-Marboxil-1985606-14-1

TSAMAISO KHABANE

Quality management1

Tlhahiso18Merero ea Tlhahlobo ea Boleng e amohetsoeng4, le6merero e tlas'a tumello.

Quality management2

Sistimi e tsoetseng pele ea boleng ba machaba e thehile motheo o tiileng oa thekiso.

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Tlhokomelo ea boleng e tsamaisana le potoloho eohle ea bophelo ba sehlahisoa ho netefatsa boleng le phello ea kalafo.

Quality management4

Sehlopha sa Litaba tsa Taolo ea Setsebi se tšehetsa litlhoko tsa boleng nakong ea kopo le ngoliso.

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