China Chlorothiazide baetsi le bafani ba thepa |CPF

Chlorothiazide

Tlhaloso e Khutšoanyane:

Lebitso la API	Pontsho	Tlhaloso	US DMF	EU DMF	CEP
Chlorothiazide	Li-diuretics	USP/EP

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Ka morao

Chlorothiazide ke inhibitor ea carbonic anhydrase 'me e na le matla a fokolang ho feta acetazolamide.Motsoako ona o bontšitsoe ho thibela ho tsosolosoa ha li-ion tsa sodium le chloride.

Tlhaloso

Chlorothiazide ke diuretic le antihypertensive.(IC50=3.8 mM) Sepheo: Tse ling Chlorothiazide sodium (Diuril) ke diuretic e sebelisoang sepetlele kapa bakeng sa tšebeliso ea botho ho laola metsi a mangata a amanang le ho hloleha ha pelo.E boetse e sebelisoa e le antihypertensive.Hangata e nooa ka mokhoa oa lipilisi, hangata e nooa hang kapa habeli ka letsatsi.Sebakeng sa ICU, chlorothiazide e fuoa diuretics ho mokuli ho kenyelletsa furosemide (Lasix).E sebetsa ka mokhoa o fapaneng ho feta furosemide, 'me e kenngoa ka mokhoa o ts'oanelang e le ho emisoa ho tsosolositsoeng ho tsamaisoa ka nasogastric tube (NG tube), lithethefatsi tsena tse peli li ka khona ho tse ling.

Teko ea Tleliniki

Nomoro ea NCT	Motšehetsi	Boemo	Letsatsi la qalo	Mokhahlelo
NCT03574857	Univesithi ea Virginia	Ho hloleha ha pelo	Phuptjane 2018	Mokhahlelo oa 4
NCT02546583	Univesithi ea Yale\|Setsi sa Naha sa Pelo, Matšoafo le Mali (NHLBI)	Ho hloleha ha Pelo	Phato 2015	Ha e sebetse
NCT02606253	Univesithi ea Vanderbilt \| Setsi sa Bongaka sa Univesithi ea Vanderbilt	Ho hloleha ha Pelo	Hlakola 2016	Mokhahlelo oa 4
NCT00004360	Setsi sa Naha sa Mehloli ea Lipatlisiso (NCRR)\|Univesithi ea Leboea-bophirimela\|Ofisi ea Mafu a Rarehang (ORD)	Lefu la tsoekere la Insipidus, Nephrogenic	September 1995
NCT00000484	Setsi sa Naha sa Pelo, Matšoafo le Mali (NHLBI)	Mafu a pelo \| Mafu a pelo \| Khatello ea mali \| Mafu a Vascular	Mmesa 1966	Mokhahlelo oa 3