Crisaborole

Tlhaloso e Khutšoanyane:

Lebitso la API Pontsho Moqapi Letsatsi la Phello ea Patent(US)
Crisaborole Dermatitis ea Atopic le Eczema Pfizer La 11 Phuptjane 2026 


Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

TLHAKISO SEHLAHISO

Crisaborole ke setho sa sehlopha sa benzoxaboroles e leng 5-hydroxy-1,3-dihydro-2,1-benzoxaborole eo ho eona phenolic.haedrojenee nketsoe sebaka ke sehlopha sa 4-cyanophenyl.Phosphodiesterase 4 inhibitor e sebelisetsoang ho phekola dermatitis e bonolo ho isa ho e itekanetseng ho bana le batho ba baholo.E na le karolo ea phosphodiesterase IV inhibitor, eantipsoriaticle sethethefatsi se seng sa steroidal se thibelang ho ruruha.Ke benzoxaborole, ether e nkhang hamonate le nitrile.

Crisaborole ke buka ea lipaleoxaborolee amohetsoe ke FDA ka la 14 Tšitoe, 2016 joalo ka Eucrisa, kalafo ea mantlha ea dermatitis e bobebe ho isa ho e itekanetseng ea atopic.Sehlahisoa sena se seng sa steroidal se sebetsa hantle ho ntlafatseng ho teba ha mafu, ho fokotsa kotsi ea tšoaetso le ho fokotsa matšoao ho bakuli ba lilemo tse 2 ho ea holimo.E fokotsa ho ruruha ha sebaka sa letlalo 'me e thibela ho mpefala ho eketsehileng ha lefu lena ka mokhoa o motle oa tšireletso.Sebopeho sa eona se na le aboroneathomo, e thusang ho kenella ha letlalo le ho tlama ho setsi sa bimetal sa phosphodiesterase 4 enzyme.Hajoale e ntse e ntlafatsoa joalo ka kalafo ea lihlooho tsa psoriasis.

Crisaborole ke Phosphodiesterase 4 Inhibitor.Mokhoa oa ts'ebetso ea crisaborole ke Phosphodiesterase 4 Inhibitor.

TSAMAISO KHABANE

Quality management1

Tlhahiso18Merero ea Tlhahlobo ea Boleng e amohetsoeng4, le6merero e tlas'a tumello.

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Sistimi e tsoetseng pele ea boleng ba machaba e thehile motheo o tiileng oa thekiso.

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Tlhokomelo ea boleng e tsamaisana le potoloho eohle ea bophelo ba sehlahisoa ho netefatsa boleng le phello ea kalafo.

Quality management4

Sehlopha sa Litaba tsa Taolo ea Setsebi se tšehetsa litlhoko tsa boleng nakong ea kopo le ngoliso.

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