Crisaborole

Tlhaloso e Khutšoanyane:

Lebitso la API Pontsho Moqapi Letsatsi la Phello ea Patent(US)
Crisaborole Dermatitis ea Atopic le Eczema Pfizer La 11 Phuptjane 2026 


Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

TLHOKOMELO SEHLAHISO

Crisaborole ke setho sa sehlopha sa benzoxaboroles e leng 5-hydroxy-1,3-dihydro-2,1-benzoxaborole eo ho eona phenolic.haedrojenee nketsoe sebaka ke sehlopha sa 4-cyanophenyl. Phosphodiesterase 4 inhibitor e sebelisetsoang ho phekola dermatitis e bonolo ho isa ho e itekanetseng ho bana le batho ba baholo. E na le karolo ea phosphodiesterase IV inhibitor, eantipsoriaticle sethethefatsi se seng sa steroidal se thibelang ho ruruha. Ke benzoxaborole, ether e nkhang hamonate le nitrile.

Crisaborole ke buka ea lipaleoxaborolee amohetsoe ke FDA ka la 14 Tšitoe, 2016 joalo ka Eucrisa, kalafo ea mantlha ea dermatitis e bobebe ho isa ho e itekanetseng ea atopic. Sethethefatsi sena se seng sa steroidal se sebetsa hantle ho ntlafatseng ho teba ha mafu, ho fokotsa kotsi ea tšoaetso le ho fokotsa matšoao ho bakuli ba lilemo tse 2 ho ea holimo. E fokotsa ho ruruha ha sebaka sa letlalo 'me e thibela ho mpefala ha lefu lena ka mokhoa o motle oa tšireletso. Sebopeho sa eona se na le aboroneathomo, e thusang ho kenella ha letlalo le ho tlama setsing sa bimetal sa phosphodiesterase 4 enzyme. Hajoale e ntse e ntlafatsoa joalo ka kalafo ea lihlooho tsa psoriasis.

Crisaborole ke Phosphodiesterase 4 Inhibitor. Mokhoa oa ts'ebetso oa crisaborole ke Phosphodiesterase 4 Inhibitor.

TS'ELISO TS'OANELO

Tsamaiso ea boleng1

Tlhahiso18Merero ea Tlhahlobo ea Boleng e amohetsoeng4, le6merero e tlas'a tumello.

Tsamaiso ea boleng2

Sistimi e tsoetseng pele ea taolo ea boleng ba machabeng e ralile motheo o tiileng oa thekiso.

Tsamaiso ea boleng3

Tlhokomelo ea boleng e tsamaisana le potoloho eohle ea bophelo ba sehlahisoa ho netefatsa boleng le phello ea kalafo.

Tsamaiso ea boleng4

Sehlopha sa Litaba tsa Taolo ea Setsebi se tšehetsa litlhoko tsa boleng nakong ea kopo le ngoliso.

TS'ELISO TS'OANELO

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Mochini oa Sejeremane oa Fette Compacting

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