Relugolix e sebelisoa ho phekola mofetše oa senya ho banna.
Mabitso a Brand: Orgovyx
Sehlopha sa Lithethefatsi: Antineoplastic - LHRH (GnRH) Antagonist Pituitary Suppressants
Ho fumaneha: Lengolo la ngaka lea Hlokahala
Boimana: Ikopanye le ngaka ea hau.Meriana ena e ka ba kotsi ho lesea le e-s'o tsoaloe.
Lactation: Ikopanye le ngaka pele u sebelisa

Relugolix ke mohanyetsi ea fumanehang ka molomo, eseng peptide gonadotropin-release hormone (GnRH kapa luteinizing hormone-releasing hormone (LHRH)) ), e nang le ts'ebetso e ka 'nang ea e-ba teng ea antineoplastic.Relugolix ka tlholisano e tlama le ho thibela moamoheli oa GnRH ka har'a tšoelesa ea anterior pituitary, eo ka bobeli e thibelang GnRH ho tlama ho moamoheli oa GnRH le ho thibela secretion le ho lokolloa ha lihomone tsa luteinizing (LH) le follicle stimulating hormone (FSH).Ho banna, ho thibela tlhahiso ea LH ho thibela ho lokolloa ha testosterone liseleng tsa Leydig ka har'a testes.Kaha testosterone ea hlokahala ho boloka tšoelesa ea senya, ho fokotsa maemo a testosterone ho ka thibela ho ata ha lisele tsa kankere ea tšoelesa ea senya e itšetlehileng ka lihomone.

Relugolix ke mohanyetsi oa gonadotropin-release hormone (GnRH) receptor antagonist e sebelisoang ho phekola maemo a 'maloa a arabelang lihomone.E ile ea amoheloa ka lekhetlo la pele Japane ka 2019, tlasa lebitso la Relumina, bakeng sa kalafo ea matšoao a uterine fibroids, mme haufinyane tjena ke United States 'FDA ka 2020, tlasa lebitso la Orgovyx, bakeng sa kalafo ea mofets'e o tsoetseng pele oa senya.Relugolix e boetse e ithutoa kalafo ea matšoao a endometriosis.Relugolix ke mohanyetsi oa pele ('me hajoale ke eena feela) ea tsamaisoang ka molomo oa GnRH e amoheloang bakeng sa kalafo ea mofets'e oa senya - liphekolo tse ts'oanang joalo ka [degarelix] li hloka tsamaiso ea subcutaneous - ka hona e fana ka khetho ea kalafo e boima ho bakuli ba neng ba ka hloka ho etela tleliniking. bakeng sa tsamaiso ke litsebi tsa tlhokomelo ea bophelo.Ntle le boiketlo ba eona ba ho sebelisa, relugolix e ile ea bontšoa e phahametse ho tepella maikutlong ha maemo a testosterone ha e bapisoa le [leuprolide], e leng phekolo e 'ngoe ea ho hloka androgen e sebelisoang ho phekola kankere ea senya.

Relugolix ke "Gonadotropin Releasing Hormone Receptor Antagonist".Mokhoa oa ts'ebetso oa relugolix o tšoana le Gonadotropin Releasing Hormone Receptor Antagonist, le Cytochrome P450 3A Inducer, le Cytochrome P450 2B6 Inducer, le Breast Cancer Resistance Protein Inhibitor, le P-Glycoprotein Inhibitor.Phello ea physiologic ea relugolix ke ka ho Fokotsa GnRH Secretion.

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